Aayush GuptaSwitchable bispecific BCMA/CD19 CAR-T cell therapy for refractory systemic lupus erythematosus
Dr Aayush Gupta leads this ₹3 crore research project, funded by Anusandhan National Research Foundation (ANRF): switchable bispecific BCMA/CD19 CAR-T cell therapy for refractory systemic lupus erythematosus. Role: principal investigator, with IIT Kanpur. Since December 2025, ongoing.
- Funder
- Anusandhan National Research Foundation (ANRF)
- Amount
- ₹3 crore (INR 3,00,00,000)
- Role
- Principal investigator, with IIT Kanpur
- Period
- Since December 2025, ongoing
- Status
- Ongoing
- Investigator
- Dr Aayush Gupta
Other grants
- CSIR-IGIB · ₹4.5 lakhSkin cell homeostasisPrincipal investigator · 2015 to 2017, completed
- Adiuvo Diagnostics · ₹3.5 lakhPortable fluorescence dermascope to identify the pathogens of skin infectionPrincipal investigator · 2019, completed
- ICMR · ₹67.8 lakhTopical transglutaminase-1 nanocomplex for enzyme replacement in autosomal recessive congenital ichthyosisPrincipal investigator, with CSIR-IGIB · 2019 to 2021, completed
- IADVL · ₹5 lakhMelanocyte and fibroblast cross-talk in keloidsPrincipal investigator · Since 2021, ongoing
- DBT · ₹85.5 lakhFully automated device that sprays a sterile bioscaffold carrying the patient’s own cellsPrincipal investigator, with CSIR-IGIB and BITS Pilani · Since 2023, ongoing
- ANRF · ₹77 lakhImmune-competent 3D human skin model of vitiligoJoint principal investigator with Dr Rohit Kothari, with CSIR-IGIB · Since December 2025, ongoing
- ICMR · ₹85 lakhSkin-on-Chip for screening cosmetic endocrine disruptors relevant to PCOSJoint principal investigator with Dr Roopesh Rai · Since September 2026, ongoing
- DBT · ₹70.82 lakhNon-viral TGM1 delivery validated in a TGM1-deficient 3D human skin modelPrincipal investigator, with CSIR-IGIB · Starts December 2026