Aayush GuptaFrom the surface to the subcutis
Seven research programmes run from the top of the skin to the bottom, from cameras that read the surface to scaffolds that rebuild the dermis.
Programmes
From the skin surface to the subcutis
- Above the skin surfaceImaging and diagnosticsA point-of-care multispectral imaging device with artificial intelligence was tested against standard care for leg ulcers in leprosy in a within-person randomised pilot trial.4 papers, 1 grants
- Stratum corneumIchthyosis and genodermatosesSevere autosomal recessive congenital ichthyosis carries a heavy psychosocial burden for patients and families, and secukinumab reduced its inflammation but improved scaling only mildly.16 papers, 2 grants
- Basal layer and melanocytesVitiligo and pigment biologyVitiligo skin carries a lower ultraviolet signature than non-melanoma skin cancers, and its epidermis shows a strong anti-skin cancer signature in miRNA networks.15 papers, 2 trials, 1 grants
- Epidermis and dermisProcedures and painIn a split-lesion study, vibration-assisted anaesthesia reduced pain during dermatologic procedures, and Qtanea Solutions now makes the vibration device, Vybe.8 papers
- Dermal nervesLeprosy and infectionHe is the principal investigator at Dr.15 papers, 2 trials
- DermisWound healing and tissue engineeringThe Bioprinting Laboratory develops injectable granular hydrogels that combine extracellular-matrix mimicry with microporosity for skin tissue engineering.2 papers, 2 grants
- The whole patientQuality of lifeIn leprosy, internalised stigma rather than disability drives the loss of quality of life.11 papers