Aayush GuptaSkin-on-Chip for screening cosmetic endocrine disruptors relevant to PCOS
Dr Aayush Gupta leads this ₹85 lakh research project, funded by Indian Council of Medical Research (ICMR): skin-on-Chip for screening cosmetic endocrine disruptors relevant to PCOS. Role: joint principal investigator with Dr Roopesh Rai. Since September 2026, ongoing.
- Funder
- Indian Council of Medical Research (ICMR)
- Amount
- ₹85 lakh (INR 85,00,000)
- Role
- Joint principal investigator with Dr Roopesh Rai
- Period
- Since September 2026, ongoing
- Status
- Ongoing
- Investigator
- Dr Aayush Gupta
Research programme
The Bioprinting Laboratory develops injectable granular hydrogels that combine extracellular-matrix mimicry with microporosity for skin tissue engineering. A DBT grant funds an automated spray device for autologous cell-grafted bioscaffolds. In vitiligo skin, miR-21-5p delays wound healing by regulating PDCD4 and Maspin.
Related papers
2 in this area
- Bioorthogonally reinforced injectable granular hydrogels synergizing ECM mimicry with microporosity for skin tissue engineeringBiomaterials Science2026DOI
- Differential regulation of miR-21-5p delays wound healing of melanocyte-deprived vitiligo skin by modulating the expression of tumor-suppressors PDCD4 and MaspinJournal of Cellular Physiology2021DOI
Other grants
- CSIR-IGIB · ₹4.5 lakhSkin cell homeostasisPrincipal investigator · 2015 to 2017, completed
- Adiuvo Diagnostics · ₹3.5 lakhPortable fluorescence dermascope to identify the pathogens of skin infectionPrincipal investigator · 2019, completed
- ICMR · ₹67.8 lakhTopical transglutaminase-1 nanocomplex for enzyme replacement in autosomal recessive congenital ichthyosisPrincipal investigator, with CSIR-IGIB · 2019 to 2021, completed
- IADVL · ₹5 lakhMelanocyte and fibroblast cross-talk in keloidsPrincipal investigator · Since 2021, ongoing
- DBT · ₹85.5 lakhFully automated device that sprays a sterile bioscaffold carrying the patient’s own cellsPrincipal investigator, with CSIR-IGIB and BITS Pilani · Since 2023, ongoing
- ANRF · ₹3 croreSwitchable bispecific BCMA/CD19 CAR-T cell therapy for refractory systemic lupus erythematosusPrincipal investigator, with IIT Kanpur · Since December 2025, ongoing
- ANRF · ₹77 lakhImmune-competent 3D human skin model of vitiligoJoint principal investigator with Dr Rohit Kothari, with CSIR-IGIB · Since December 2025, ongoing
- DBT · ₹70.82 lakhNon-viral TGM1 delivery validated in a TGM1-deficient 3D human skin modelPrincipal investigator, with CSIR-IGIB · Starts December 2026